Source: http://www.aloe.com/why.html 1989 Researchers from Okinawa, Japan reported in the Japanese Journal of Cancer Research, that Aloe contained at least three anti-tumor agents, emodin, mannose, and lectin. The researchers concluded that Aloe controls pulmonary carcinogenesis and is effective in the treatment of leukemia and sarcoma and that it would prevent the development of tumors. 1991 Ian R. Tizard, PhD, of Texas A&M, reported in the Journal of Molecular BBiotherapy, that Aloe mannose was highly effective against feline leukemia and soft tissue cancer in cats and dogs. 1992 Dr. James Duke, United States Department of Agriculture, approved the use of Aloe mannose as a treatment of soft tissue cancer in animals and feline leukemia. Source: http://infinity.dorsai.org/Naturopathic.Physician/articles.lay cancer.botanicals.JS.html LILIACEAE FAMILY Aloe has been shown to be prophylactic, and possibly therapeutic to cobalt 60 induced leukopenia. Aloe may also have an anti-sarcoma effect. 2, 3, 4 A long chained mannan polymer known as Acemannan has been found to have immunostimulatory properties and is used parenterally in veterinary medicine for feline leukemia and fibrosarcoma. 45,46 It is thought that Acemannan stimulates macrophages to release Tumor Necrosis Factor, interleukin and interferon. The consumption of 1/2 to 1 liter of aloe vera juice appears to be the necessary therapeutic dosage for humans. 46. Sheets MA, et al, Studies of the effects of acemannan on retrovirus infections: Clinical stabilization of feline leukemia virus-infected cats. Mol Biother 3(1):41-5, 1991