g. Anecdotal reports of revision to FIV-Ab negative status may justify
periodic reevaluation by Western Blot or IFA.
h. Because seroconversion may not take place before 3 to 4 months or longer post infection,
reassessment of FIV-Ab status is justified. Additionally, kittens less
than 16 weeks of age are presumed to have diminished immune response as
compared to normal adult cats; this may enhance the likelihood that
exposure to FIV will result in infection. This increased risk of
infection could justify reevaluation of a negative FIV-Ab test depending
on the kitten's historical exposure status.
i. It is emphasized that FIV
infection generally carries a more favorable prognosis, both with regard
to longevity and relative immune function, than does infection with FeLV.
Therefore, a continued positive FIV-Ab status has uncertain relevance to
the prognosis and therapeutic management of the cat.
j. Verification of FIV-Ab status is arguably more relevant as it influences viral transmission
to other cats. If the sick FIV-infected cat recovers from its current
illness, subsequent testing may be justified concurrently with routine
illness prevention programs (e.g. geriatric profile) since revision to
seronegativity has been anecdotally reported.
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